Things I do when running The Sprawl.
I write my Legwork and Action Clocks so that they are location agnostic or target the team directly. So it will say something like, "Any facility controlled by the corp has armed security posted." OR "Hugo The Butcher personally tracks down the PCs."
I word my mission Objectives in terms of key decisions. So I might say, "When the players decide what to do with the probe, mark XP"
I always assume the players can get paid, just maybe not by their original employer. So, if they go for a double cross you will still roll Get Paid even if that means you get approached by a mysterious stranger who thanks you for serving their interests and will be speaking again with them in the future.
This is because I treat all corps ultimately as omniscient gods. The PCs can't hide from everyone at all times and if I corp doesn't know what you're up to, it's only because they aren't looking. That's why you can write Legwork and Action clocks at all. It don't matter what the PCs do, when they attract attention they WILL find you.
To me, "mission based" and "play to find out" are not at odds. Just slightly constrained. Combined it reads like this, "play to find out how the players do the mission." You give them a mission. Now we play to find out how that goes down. That's The Sprawl.
Hope that was useful.
RE: Running The Sprawl: First impressions