Since Forknote made it really easy to create new coins, there has been constant fight against coin developers and miners with powerful Xeon clusters, FCPGA chips and ASIC devices. There is three main methods

Users of several forknote-based coins have noticed their daemons getting stuck for several hours while trying to keep blockchain synchronized. Throrough investigation have lead the main culprit being a

Previously people could restore CryptoNote daemons and miners from quarantine of virus scanners running on Windows, but recent updates remove this feature. It is still possible to whitelist directories